Publications

Simtomax® has been trialed in multiple clinical studies, with both prospective and retrospective setups. To date, clinical validation on several hundreds of patients has shown the outstanding performance of the test, and its exceptional value for early screening-out of Celiac Disease.

Clinical Studies

Study comparing Simtomax® to IgA/IgG tTG ELISA in a pediatric and adult population considered at high risk for celiac disease – 112 patientspubmed Download
Study comparing Simtomax® to IgA/IgG tTG ELISA in a pediatric population considered at high risk for celiac disease – 250 patientspubmed  Download
Study comparing Simtomax® to diagnosis by IgA/IgG tTG ELISA/biopsy/patient follow-up in a IgA deficient pediatric populationgjjhdicg  Download
Study evaluating the diagnostic accuracy of Simtomax® compare to IgA tTG ELISA as a measure of compliance to gluten free diet in adults with celiac disease – 82 patientsBMJ  Download
Study comparing Simtomax® to IgA tTG ELISA/EMA/duodenal biopsy in a pediatric population presenting gastrointestinal symptoms – 53 patients

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Study evaluating the diagnostic accuracy of Simtomax®, EMA and IgA tTG ELISA compare to biopsy as a measure of compliance to gluten free diet in adults with celiac disease – 43 patients to date, ongoing  Download
Study evaluating the diagnostic accuracy of Simtomax®, EMA and IgA tTG ELISA compare to biopsy in an adult population of patients referred for gastroscopy from primary and secondary care – 354 patients to date, ongoing  Download
Study evaluating the diagnostic accuracy of Simtomax® compare to IgA/IgG DGP ELISA as a measure of compliance to gluten free diet in adults with celiac disease – 46 patients  Download

Reviews and Cost-Benefit Studies

Cost-Benefit analysisBJHM Download
Expert opinion on Simtomax®pubmed Download